Pedalitin 6-O-glucoside

Research use only, not for human use.

Pedaliin is a bioactive component obtained from the ethanol extract of Sesame (Sesamum indicum L.) leaves (SLs). Pedaliin shows in vitro antioxidant and anti-colon cancer efficacy with radical scavenging activity and ferric reducing antioxidant power (FRAP).

Pedaliin is a bioactive component obtained from the ethanol extract of Sesame (Sesamum indicum L.) leaves (SLs). Pedaliin shows in vitro antioxidant and anti-colon cancer efficacy with radical scavenging activity and ferric reducing antioxidant power (FRAP).

Pedaliin (0-35 μM; 72 h) dose-dependently attenuates the growth of human colon cancer cells, HT29 and HCT116.Pedaliin (3.5-35 μM; 30 min; 37 ℃) has ferric reducing antioxidant power (FRAP). Pedaliin (7 μM; 48 h) alleviates invasion and migration of HT29 and HCT116 cells in non-cytotoxic conditions.Pedaliin (20 μL) shows high 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, oxygen radical absorbance capacity (ORAC), and in vitro antiglycation activities, and inhibits BSA glycation with an IC50 value of 41.8 μM.Cell Viability Assay Cell Line:HCT116 cells Concentration:0, 3.5, 7, 17.5, and 35 μM Incubation Time:48 hours or 72 hours Result:Inhibited cell growth (72 h) by 24% at 3.5-35 μM, invasion (48 h) by 18% at 7 μM, and migration (48 h) by 33% at 7 μM.

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Others

Other Targets

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22860-72-6

478.4

C22H22O12

>98% (HPLC)

DMSO : ≥ 50 mg/mL (104.52 mM; )

OC1=C2C(OC(=CC2=O)C3=CC(O)=C(O)C=C3)=CC(OC)=C1O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O

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(-20℃)

With Ice Pack

≥ 2 years