Ac-GRP (20-26) (human, porcine, canine)

Bintrafusp alfa (M7824) is a bifunctional fusion protein consisting of the extracellular structural domain of TGF-βRII (a TGF-β “trap”) fused to a monoclonal antibody against human immunoglobulin G1 fused to programmed death ligand 1 (PD-L1).

Phenylacetylglutamine is a normal constituent of human urine but other mammals such as the dog cat rat monkey sheep and horse do not excrete this compound. Phenylacetylglutamine is a major nitrogenous metabolite that accumulates in uremia. Phenylacetylglutamine also is a microbial metabolite found in Christensenellaceae Lachnospiraceae and Ruminococcaceae.