Homocitrulline is a metabolite that can be detected in larger amounts in the urine of individuals with urea cycle disorders. The accumulation of carbamyl phosphate due to a depleted supply of ornithine for the urea cycle may be responsible for the enhanced synthesis of homocitrulline and homoarginine in some cases.

Deoxyvasicinone derivatives can be considered as promising lead molecules for the development of more potent inhibitors of NEDD8-activating enzyme.

The herbs of Cryptolepis sanguinolenta.