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Villocarine A
CAS No. 1319743-81-1
Villocarine A( ——— )
Catalog No. M38182 CAS No. 1319743-81-1
Villocarine A is a natural vasorelaxant indole alkaloid.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameVillocarine A
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NoteResearch use only, not for human use.
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Brief DescriptionVillocarine A is a natural vasorelaxant indole alkaloid.
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DescriptionVillocarine A is a natural vasorelaxant indole alkaloid.
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In VitroVillocarine A exhibited excellent activity during the initial stage, within 10-30 min after injection, with potent vasorelaxant effects observed at 30 μM against PE-mediated contraction in a rat aorta. Villocarine A exhibited a moderate level of inhibition at 30 μM against PE and 1 μM-induced contraction of the aortic rings in the presence of nicardipine (1 μM) in a Ca2+-free medium.
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In Vivo———
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Synonyms———
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PathwayOthers
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TargetOther Targets
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Recptor———
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Research Area———
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Indication———
Chemical Information
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CAS Number1319743-81-1
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Formula Weight366.45
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Molecular FormulaC22H26N2O3
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Purity>98% (HPLC)
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Solubility———
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hirotaka Matsuo, et al. New vasorelaxant indole alkaloids, villocarines A-D from Uncaria villosa. Bioorg Med Chem. 2011 Jul 1;19(13):4075-9.?2. Faisal Omar, et al. Plant-Based Indole Alkaloids: A Comprehensive Overview from a Pharmacological Perspective. Molecules. 2021 Apr 15;26(8):2297.?
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