Villocarine A( ——— )

Catalog No. M38182 CAS No. 1319743-81-1

Villocarine A is a natural vasorelaxant indole alkaloid.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Villocarine A
Note

Research use only, not for human use.
Brief Description

Villocarine A is a natural vasorelaxant indole alkaloid.
Description

Villocarine A is a natural vasorelaxant indole alkaloid.
In Vitro

Villocarine A exhibited excellent activity during the initial stage, within 10-30 min after injection, with potent vasorelaxant effects observed at 30 μM against PE-mediated contraction in a rat aorta. Villocarine A exhibited a moderate level of inhibition at 30 μM against PE and 1 μM-induced contraction of the aortic rings in the presence of nicardipine (1 μM) in a Ca2+-free medium.
In Vivo

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Synonyms

———
Pathway

Others
Target

Other Targets
Recptor

———
Research Area

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Indication

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Chemical Information

CAS Number

1319743-81-1
Formula Weight

366.45
Molecular Formula

C22H26N2O3
Purity

>98% (HPLC)
Solubility

———
SMILES

———
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Hirotaka Matsuo, et al. New vasorelaxant indole alkaloids, villocarines A-D from Uncaria villosa. Bioorg Med Chem. 2011 Jul 1;19(13):4075-9.?2. Faisal Omar, et al. Plant-Based Indole Alkaloids: A Comprehensive Overview from a Pharmacological Perspective. Molecules. 2021 Apr 15;26(8):2297.?

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