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FC131 TFA
CAS No. 842166-42-1
FC131 TFA ( —— )
Catalog No. M37915 CAS No. 842166-42-1
FC131 TFA (606968-52-9 free base) (FC131 TFA) is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hiv activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 73 | Get Quote |
|
| 5MG | 117 | Get Quote |
|
| 10MG | 187 | Get Quote |
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| 25MG | 305 | Get Quote |
|
| 50MG | 456 | Get Quote |
|
| 100MG | 624 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameFC131 TFA
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NoteResearch use only, not for human use.
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Brief DescriptionFC131 TFA (606968-52-9 free base) (FC131 TFA) is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hiv activity.
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DescriptionFC131 TFA is a CXCR4 antagonist, inhibits [125I]-SDF-1 binding to CXCR4, with an IC50 of 4.5 nM. Anti-HIV activity.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAutophagy
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TargetCXCR
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RecptorCXCR | HIV Protease
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Research Area——
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Indication——
Chemical Information
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CAS Number842166-42-1
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Formula Weight843.85
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Molecular FormulaC38H48F3N11O8
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (296.26 mM; Ultrasonic )
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SMILESFC(F)(F)C(=O)O.N=C(N)NCCC[C@@H]4NC(=O)[C@@H](NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](Cc2cc3ccccc3cc2)NC4=O)CCCNC(=N)N
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Tamamura H, et al. Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131. J Med Chem. 2005 Jan 27;48(2):380-91.?
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