N6-Bz-5-O-DMTr-3-deoxyadenosine-2-O-CED-phosphoramidite( —— )

Catalog No. M37907 CAS No. 207347-42-0

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MSDS

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Product Name

N6-Bz-5-O-DMTr-3-deoxyadenosine-2-O-CED-phosphoramidite
Note

Research use only, not for human use.
Brief Description

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite, an adenine nucleoside analog, has potential vasodilator and anticancer activities relevant to cancer research.
Description

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
In Vitro

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In Vivo

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Synonyms

——
Pathway

Microbiology/Virology
Target

Antibiotic
Recptor

Nucleoside Antimetabolite/Analog
Research Area

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Indication

——

CAS Number

207347-42-0
Formula Weight

857.93
Molecular Formula

C47H52N7O7P
Purity

>98% (HPLC)
Solubility

——
SMILES

C(OC[C@H]1O[C@H]([C@H](OP(N(C(C)C)C(C)C)OCCC#N)C1)N2C=3C(N=C2)=C(NC(=O)C4=CC=CC=C4)N=CN3)(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7
Chemical Name

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1. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.?

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