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2,5-Difluoro-2-deoxy-1-arabinosyluracil

CAS No. 69123-95-1

2,5-Difluoro-2-deoxy-1-arabinosyluracil( —— )

Catalog No. M37886 CAS No. 69123-95-1

2',5-Difluoro-2'-deoxy-1-arabinosyluracil (2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine) is a urinary pyrimidine nucleoside analogue with potential antiepileptic and antihypertensive activity, which can be used to study anticonvulsant and anxiety disorders.

Purity : >98% (HPLC)

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HPLC

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10MG	31	In Stock
25MG	51	In Stock
50MG	75	In Stock
100MG	112	In Stock
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Biological Information

Product Name

2,5-Difluoro-2-deoxy-1-arabinosyluracil
Note

Research use only, not for human use.
Brief Description

2',5-Difluoro-2'-deoxy-1-arabinosyluracil (2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine) is a urinary pyrimidine nucleoside analogue with potential antiepileptic and antihypertensive activity, which can be used to study anticonvulsant and anxiety disorders.
Description

5-Fluoro-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (2',5-difluoro-2'-deoxy-1-arabinosyluracil) is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Microbiology/Virology
Target

Antibiotic
Recptor

Nucleoside Antimetabolite/Analog
Research Area

——
Indication

——

Chemical Information

CAS Number

69123-95-1
Formula Weight

264.18
Molecular Formula

C9H10F2N2O5
Purity

>98% (HPLC)
Solubility

——
SMILES

F[C@@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(F)=C2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.?

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