2-O-(2-Azidoethyl)adenosine

CAS No. 2226475-42-7

2-O-(2-Azidoethyl)adenosine( —— )

Catalog No. M37885 CAS No. 2226475-42-7

2'-O-(2-azidoethyl)adenosine is a purine nucleoside analog with potential antitumor activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    2-O-(2-Azidoethyl)adenosine
  • Note
    Research use only, not for human use.
  • Brief Description
    2'-O-(2-azidoethyl)adenosine is a purine nucleoside analog with potential antitumor activity.
  • Description
    2’-O-(2-Azidoethyl)adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. 2’-O-(2-Azidoethyl)adenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antibiotic
  • Recptor
    Nucleoside Antimetabolite/Analog
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2226475-42-7
  • Formula Weight
    336.31
  • Molecular Formula
    C12H16N8O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O(CCN=[N+]=[N-])[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CO)[C@H]1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.?
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