Trombodipine

Research use only, not for human use.

Trombodipine (PCA-4230) is a platelet aggregation inhibitor with antithrombotic activity and protection against Listeria monocytogenes.

Trombodipine is an antithrombotic agent.

Trombodipine is an antithrombotic agent. Exposure to 50 μM Trombodipine reveals an important stasis of growth. The percentage of inhibition exerted by 1 μM Trombodipine on day 3, 5 and 7 of the growth curve is 22.0±4.5, 32.0±3.0 and 29.4±6.0%, respectively (P<0.05). The inhibitory effect of Trombodipine on cell proliferation is reversible and after removal of Trombodipine the proliferation of the cells is resumed. Addition of Trombodipine reduces cell number in a dose-dependent manner over a period of 4 to?6 days in culture. When compare to control cultures at the latest time points investigated, 5 μM Trombodipine decreases the number of E19P cells and human VSMCs by 25 and 21%, respectively, whereas 50?μM Trombodipine reduces E19P and human VSMC number by 85 and 74%, respectively.

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Microbiology/Virology

Antibiotic

Antibiotic

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113658-85-8

448.49

C21H24N2O7S

>98% (HPLC)

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O=C(OCC)C1=C(NC(=C(C(=O)OCCN2C(=O)C=3C=CC=CC3S2(=O)=O)C1C)C)C

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(-20℃)

With Ice Pack

≥ 2 years