Cart
sales@molnova.com
4-methoxylonchocarpin
CAS No. 51589-67-4
4-methoxylonchocarpin( —— )
Catalog No. M37846 CAS No. 51589-67-4
4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 466 | In Stock |
|
| 10MG | 679 | In Stock |
|
| 25MG | 1036 | In Stock |
|
| 50MG | 1376 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Name4-methoxylonchocarpin
-
NoteResearch use only, not for human use.
-
Brief Description4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound.
-
Description4-Methoxylonchocarpin is an orally active anti-inflammatory agent. 4-methoxylonchocarpin inhibits the binding of LPS to Toll-like Receptor (TLR) TLR4 to inhibit NF-κB activation and TNF Receptor and IL-6 expression. 4-Methoxylonchocarpin also inhibits the phosphorylation of TGF-beta activated kinase 1 and TNBS-induced expression of IL-1β, IL-17A, and TNF. 4-methoxylonchocarpin can improve 2,4, 6-trinitrobenzene sulfonic acid (TNBS)-induced colitis mouse model.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetNF-κB
-
RecptorNF-κB | TNF
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number51589-67-4
-
Formula Weight336.38
-
Molecular FormulaC21H20O4
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESOC1=C2C(OC(C)(C)C=C2)=CC=C1C(/C=C/C3=CC=C(OC)C=C3)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Jang HM, et al. 4-Methoxylonchocarpin attenuates inflammation by inhibiting lipopolysaccharide binding to Toll-like receptor of macrophages and M1 macrophage polarization. Int Immunopharmacol. 2017 Apr;45:90-97.?
molnova catalog
related products
-
Nicaraven
Nicaraven, a hydroxyl radical scavenger, has neuroprotective and antivasospastic effects.
-
BAY 11-7085
An inhibitor of the expression of ICAM-1, VCAM-1, and E-selectin in human endothelial cells (IC50=5-10 uM).
-
Quinoclamine
Quinoclamine is a naphthoquinone derivative and is an NF-κB inhibitor.
