Cart
sales@molnova.com
4-methoxylonchocarpin
CAS No. 51589-67-4
4-methoxylonchocarpin( —— )
Catalog No. M37846 CAS No. 51589-67-4
4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 466 | In Stock |
|
| 10MG | 679 | In Stock |
|
| 25MG | 1036 | In Stock |
|
| 50MG | 1376 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Name4-methoxylonchocarpin
-
NoteResearch use only, not for human use.
-
Brief Description4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound.
-
Description4-Methoxylonchocarpin is an orally active anti-inflammatory agent. 4-methoxylonchocarpin inhibits the binding of LPS to Toll-like Receptor (TLR) TLR4 to inhibit NF-κB activation and TNF Receptor and IL-6 expression. 4-Methoxylonchocarpin also inhibits the phosphorylation of TGF-beta activated kinase 1 and TNBS-induced expression of IL-1β, IL-17A, and TNF. 4-methoxylonchocarpin can improve 2,4, 6-trinitrobenzene sulfonic acid (TNBS)-induced colitis mouse model.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetNF-κB
-
RecptorNF-κB | TNF
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number51589-67-4
-
Formula Weight336.38
-
Molecular FormulaC21H20O4
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESOC1=C2C(OC(C)(C)C=C2)=CC=C1C(/C=C/C3=CC=C(OC)C=C3)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Jang HM, et al. 4-Methoxylonchocarpin attenuates inflammation by inhibiting lipopolysaccharide binding to Toll-like receptor of macrophages and M1 macrophage polarization. Int Immunopharmacol. 2017 Apr;45:90-97.?
molnova catalog
related products
-
VER-50589
VER-50589 is a potent HSP90 inhibitor.
-
SP-100030
SP-100030 is a dual inhibitor of NF-κB and activator protein-1 (AP-1), demonstrating potent inhibition with IC50 values of 50 nM for both.
-
Grape Seed Extract
Grape Seed Extract is exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites (bioflavonoids and polyphenols) credited with important medicinal properties.
