Cassiaside B( —— )

Catalog No. M37733 CAS No. 13709-03-0

Cassiaside is a naphthyl ketone glycoside that inhibits BACE1 (IC50= 4.45 μM; Ki=9.85 μM).Cassiaside exhibits significant hepatoprotective effects against galactosamine injury and has potential anti-Alzheimer's disease (AD) activity.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Cassiaside B
Note

Research use only, not for human use.
Brief Description

Cassiaside is a naphthyl ketone glycoside that inhibits BACE1 (IC50= 4.45 μM; Ki=9.85 μM).Cassiaside exhibits significant hepatoprotective effects against galactosamine injury and has potential anti-Alzheimer's disease (AD) activity.
Description

Cassiaside is a naphthopyrone glucoside, shows mixed-type inhibition against BACE1 (IC50=4.45 μM; Ki=9.85 μM). Cassiaside possesses potential anti- Alzheimer's disease (AD) activity.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Beta-Secretase | BACE
Research Area

——
Indication

——

Chemical Information

CAS Number

13709-03-0
Formula Weight

420.37
Molecular Formula

C20H20O10
Purity

>98% (HPLC)
Solubility

——
SMILES

O(C=1C2=C(C=C3C(=C2O)C(=O)C=C(C)O3)C=C(O)C1)[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Jung HA, et al. Inhibitory activities of major anthraquinones and other constituents from Cassia obtusifolia against β-secretase and cholinesterases. J Ethnopharmacol. 2016;191:152-160.?

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