3-Deoxyaconitine( —— )

Catalog No. M18418 CAS No. 3175-95-9

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

3-Deoxyaconitine
Note

Research use only, not for human use.
Brief Description

3- Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization.
Description

3- Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the release of neurotransmitters and decreases the end plate potential at the neuromuscular junction.
In Vitro

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In Vivo

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Synonyms

——
Pathway

Apoptosis
Target

Apoptosis
Recptor

Others
Research Area

——
Indication

——

CAS Number

3175-95-9
Formula Weight

629.74
Molecular Formula

C34H47NO10
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (79.40 mM)
SMILES

CCN1CC2(CCC(C34C2C(C(C31)C5(C6C4CC(C6OC(=O)C7=CC=CC=C7)(C(C5O)OC)O)OC(=O)C)OC)OC)COC
Chemical Name

——

1.Derbre, S., et al.: Anal. Bioanal. Chem., 398, 1747 (2010), Li, M., et al.: J. Pharm. Biomed. Anal., 53, 1063 (2010)

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