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Thioquinapiperifil dihydrochloride
CAS No. 204077-66-7
Thioquinapiperifil dihydrochloride( —— )
Catalog No. M37660 CAS No. 204077-66-7
Thioquinapiperifil dihydrochloride is a phosphodiesterase (PDE-5) inhibitor (IC50: 0.074 nM) that is potent, selective and non-competitive for investigational maturation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 143 | In Stock |
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| 5MG | 125 | In Stock |
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| 10MG | 187 | In Stock |
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| 25MG | 304 | In Stock |
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| 50MG | 384 | In Stock |
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| 100MG | 539 | In Stock |
|
| 200MG | 710 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameThioquinapiperifil dihydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionThioquinapiperifil dihydrochloride is a phosphodiesterase (PDE-5) inhibitor (IC50: 0.074 nM) that is potent, selective and non-competitive for investigational maturation.
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DescriptionThioquinapiperifil dihydrochloride (KF31327), a potent, selective and non-competitive phosphodiesterase-5 (PDE-5, IC50 of 0.074 nM) inhibitor, is used for sexual enhancement study.
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In VitroThioquinapiperifil can be found in dietary supplements.Thioquinapiperifil dihydrochloride (KF31327) (0.1-10 μM) concentration dependently inhibits platelet aggregation. In the absence of nitroglycerin, higher concentrations 1 and 10 μM of Thioquinapiperifil dihydrochloride (KF31327) are required to inhibit platelet aggregation.Thioquinapiperifil dihydrochloride (KF31327) and shows significant increase in cyclic GMP at 10 μM. After 5 min incubation, the mean cyclic GMP levels of Thioquinapiperifil dihydrochloride (KF31327)-treated cells is 0.95±0.17 pmol/108 cells.
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetPDE
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RecptorPDE
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Research Area——
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Indication——
Chemical Information
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CAS Number204077-66-7
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Formula Weight485.05
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Molecular FormulaC24H29ClN6OS
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (239.69 mM; Ultrasonic )
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SMILESCl.Cl.CCn1c2cc3ncnc(NCc4ccccc4N4CCC(CO)CC4)c3cc2[nH]c1=S
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Nahoko Uchiyama, et al. Determination of a new type of phosphodiesterase-5 inhibitor, thioquinapiperifil, in a dietary supplement promoted for sexual enhancement. Chem Pharm Bull (Tokyo). 2008 Sep;56(9):1331-4.?
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