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GX 201
CAS No. 1788071-27-1
GX 201( —— )
Catalog No. M37645 CAS No. 1788071-27-1
GX 201 is a selective NaV1.7 inhibitor, IC50 of < 3.2 nM for hNaV1.7.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 163 | Get Quote |
|
| 5MG | 250 | Get Quote |
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| 10MG | 377 | Get Quote |
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| 25MG | 609 | Get Quote |
|
| 50MG | 877 | Get Quote |
|
| 100MG | 1188 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameGX 201
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NoteResearch use only, not for human use.
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Brief DescriptionGX 201 is a selective NaV1.7 inhibitor, IC50 of < 3.2 nM for hNaV1.7.
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DescriptionGX-201 is a selective NaV1.7 inhibitor, with an IC50 of <3.2 nM for hNaV1.7.
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In Vitro——
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In VivoAnimal Model:Wild-Type Mice.Dosage:0.3, 1, 3 mg/kg.Administration:Orally, once.Result:Produced a dose-dependent inhibition of the nociceptive events.
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetSodium Channel
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RecptorSodium Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number1788071-27-1
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Formula Weight563
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Molecular FormulaC25H27ClF4N2O4S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 62.5 mg/mL (111.01 mM; Ultrasonic )
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SMILESCS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2CCN(Cc3cc(ccc3Cl)C(F)(F)F)CC2)cc1F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Girish Bankar, et al. Selective Na V 1.7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic Pain. Cell Rep. 2018 Sep 18;24(12):3133-3145.?
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