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Dehydromiltirone

CAS No. 116064-77-8

Dehydromiltirone( —— )

Catalog No. M30947 CAS No. 116064-77-8

Dehydromiltirone has antioxidant activity, it shows significant anti-neuroinflammatory effects through inhibiting PI3K/Akt phosphorylation and then inhibiting NF-κB signaling pathway.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Dehydromiltirone
  • Note
    Research use only, not for human use.
  • Brief Description
    Dehydromiltirone has antioxidant activity, it shows significant anti-neuroinflammatory effects through inhibiting PI3K/Akt phosphorylation and then inhibiting NF-κB signaling pathway.
  • Description
    Dehydromiltirone has antioxidant activity, it shows significant anti-neuroinflammatory effects through inhibiting PI3K/Akt phosphorylation and then inhibiting NF-κB signaling pathway.
  • In Vitro
    Western Blot Analysis Cell Line:Kupffer cells Concentration:100?μg/mL Incubation Time:For 24?h Result:Significantly decreased p38 and p-p38 levels, NF-κBp65, IκB, andc-fos protein levels.
  • In Vivo
    Animal Model:Rat model of acute liver injury Dosage:50 mg/kg, 100 mg/kg, and 200?mg/kg Administration:p.o.; daily; for five consecutive days Result:Protected liver from CCl4-induced damage.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    116064-77-8
  • Formula Weight
    282.38
  • Molecular Formula
    C19H20O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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