ACBI3

CAS No. 2938169-76-5

ACBI3( —— )

Catalog No. M37580 CAS No. 2938169-76-5

ACBI3 (compound 7), a pan-KRAS degrader, effectively accomplishes the in vivo degradation of oncogenic KRAS .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 1036 In Stock
5MG 629 In Stock
10MG 943 In Stock
25MG 1606 In Stock
50MG 2195 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ACBI3
  • Note
    Research use only, not for human use.
  • Brief Description
    ACBI3 (compound 7), a pan-KRAS degrader, effectively accomplishes the in vivo degradation of oncogenic KRAS .
  • Description
    ACBI3 (compound 7) is a pan-KRAS degrader. ACBI3 achieves in vivo degradation of oncogenic KRAS.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2938169-76-5
  • Formula Weight
    1019.25
  • Molecular Formula
    C50H62N14O6S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C[C@]1(C2=C(SC(N)=C2C#N)CCC1)C3=NC(=NO3)C4=NC(=NC=C4)N5[C@@H](C)CN(CCCCOC6=CN([C@H](C(=O)N7[C@H](C(N[C@@H](CO)C8=CC=C(C=C8)C=9SC=NC9C)=O)C[C@@H](O)C7)C(C)C)N=N6)CCC5
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Chuan Zhou,et al. Discovery of the First-in-Class Agonist-Based SOS1 PROTACs Effective in Human Cancer Cells Harboring Various KRAS Mutations. J Med Chem. 2022, 65, 5.?
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