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ACBI3
CAS No. 2938169-76-5
ACBI3( —— )
Catalog No. M37580 CAS No. 2938169-76-5
ACBI3 (compound 7), a pan-KRAS degrader, effectively accomplishes the in vivo degradation of oncogenic KRAS .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 1036 | In Stock |
|
| 5MG | 629 | In Stock |
|
| 10MG | 943 | In Stock |
|
| 25MG | 1606 | In Stock |
|
| 50MG | 2195 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameACBI3
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NoteResearch use only, not for human use.
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Brief DescriptionACBI3 (compound 7), a pan-KRAS degrader, effectively accomplishes the in vivo degradation of oncogenic KRAS .
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DescriptionACBI3 (compound 7) is a pan-KRAS degrader. ACBI3 achieves in vivo degradation of oncogenic KRAS.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number2938169-76-5
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Formula Weight1019.25
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Molecular FormulaC50H62N14O6S2
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Purity>98% (HPLC)
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Solubility——
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SMILESC[C@]1(C2=C(SC(N)=C2C#N)CCC1)C3=NC(=NO3)C4=NC(=NC=C4)N5[C@@H](C)CN(CCCCOC6=CN([C@H](C(=O)N7[C@H](C(N[C@@H](CO)C8=CC=C(C=C8)C=9SC=NC9C)=O)C[C@@H](O)C7)C(C)C)N=N6)CCC5
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chuan Zhou,et al. Discovery of the First-in-Class Agonist-Based SOS1 PROTACs Effective in Human Cancer Cells Harboring Various KRAS Mutations. J Med Chem. 2022, 65, 5.?
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