FM1-43
CAS No. 149838-22-2
FM1-43( —— )
Catalog No. M37567 CAS No. 149838-22-2
FM1-43 is a highly lipophilic, water-soluble styrene dye that acts as an osmotic blocker of hair cell mechanical transducer channels and can be used to study neuropeptide granule dynamics and cytotoxicity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 275 | In Stock |
|
| 10MG | 411 | In Stock |
|
| 25MG | 655 | In Stock |
|
| 50MG | 908 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameFM1-43
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NoteResearch use only, not for human use.
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Brief DescriptionFM1-43 is a highly lipophilic, water-soluble styrene dye that acts as an osmotic blocker of hair cell mechanical transducer channels and can be used to study neuropeptide granule dynamics and cytotoxicity.
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DescriptionFM1-43 is a very lipophilic, water-soluble styrene dyes, can specifically bind to cell membranes and inner membrane organelles to produce fluorescence. FM1-43 is widely used in endocytic and exospic membrane structure markers.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number149838-22-2
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Formula Weight611.54
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Molecular FormulaC30H49Br2N3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (81.76 mM; Ultrasonic (<60°C)
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SMILES[Br-].[Br-].CCCCN(CCCC)c1ccc(C=Cc2cc[n+](CCC[N+](CC)(CC)CC)cc2)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Syk Inhibitor II hyd...
The impact of spleen tyrosine kinase (Syk) signaling might be prominent in lupus because (i) Syk is a shared downstream signaling molecule among circulating immune complex, LPS, and (1→3)-β-D-glucan (BG), and (ii) all of these factors are detectable in the serum of Fc gamma receptor IIb-deficient (FcgRIIb-/-) mice with sepsis. Syk inhibition downregulated several inflammatory pathways in FcgRIIb-/- macrophages activated with BG + LPS suggesting the potential anti-inflammatory impact of Syk inhibitors in lupus.
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