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Bergaptol
CAS No. 486-60-2
Bergaptol( 5-Hydroxypsoralen | 4-Hydroxybergapten )
Catalog No. M18628 CAS No. 486-60-2
Bergaptol is a potent inhibitor of debenzylation activity of CYP3A4 enzyme.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 47 | In Stock |
|
| 5MG | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBergaptol
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NoteResearch use only, not for human use.
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Brief DescriptionBergaptol is a potent inhibitor of debenzylation activity of CYP3A4 enzyme.
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DescriptionBergaptol shows very good radical scavenging activity. Bergaptol is a potent inhibitor of debenzylation activity of CYP3A4 enzyme.
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In VitroWestern Blot Analysis Cell Line:LPS-induced RAW264.7 cells Concentration:50 μg/mL Incubation Time:24 h Result:Inhibited JNK phosphorylation and NF-κB activation.Inhibited NF-κB P65 translocation from the cytosol to nucleus.
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In VivoAnimal Model:LPS (40 μg/kg, i.c.v.)-treated miceDosage:10-40 mg/kg Administration:i.p., once a day for two week Result:Reduced LPS-induced fixation and cleavage of neuronal nuclei in the CA1 region of the hippocampus (H&E staining).Increasead the dendritic spine density of mice.Inhibited LPS-induced neuroinflammation.
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Synonyms5-Hydroxypsoralen | 4-Hydroxybergapten
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number486-60-2
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Formula Weight202.16
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Molecular FormulaC11H6O4
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 50 mg/mL 247.33 mM; H2O : < 0.1 mg/mL
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SMILESC1=CC(=O)OC2=CC3=C(C=CO3)C(=C21)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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