VVD-214
CAS No. 3026500-20-6
VVD-214( —— )
Catalog No. M37551 CAS No. 3026500-20-6
VVD-214 (RO7589831) is a WRN deconjugating enzyme lethal variant inhibitor with potential antitumor activity, inhibits ATP hydrolysis and deconjugating enzyme activity, and can be used in the study of proliferative diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 167 | In Stock |
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| 5MG | 150 | In Stock |
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| 10MG | 236 | In Stock |
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| 25MG | 377 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameVVD-214
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NoteResearch use only, not for human use.
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Brief DescriptionVVD-214 (RO7589831) is a WRN deconjugating enzyme lethal variant inhibitor with potential antitumor activity, inhibits ATP hydrolysis and deconjugating enzyme activity, and can be used in the study of proliferative diseases.
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DescriptionVVD-214 (RO7589831) is a WRN deconjugating enzyme lethal variant inhibitor with potential antitumor activity, inhibits ATP hydrolysis and deconjugating enzyme activity, and can be used in the study of proliferative diseases.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorDNA/RNA Synthesis
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Research Area——
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Indication——
Chemical Information
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CAS Number3026500-20-6
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Formula Weight437.46
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Molecular FormulaC20H21F2N3O4S
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Purity>98% (HPLC)
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Solubility——
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SMILESO(C=1C(C(N[C@H](/C=C/S(C)(=O)=O)C2CC2)=O)=CN=C(C(C)(F)F)N1)C3=CC=CC=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Asiaticoside
Asiaticoside (Madecassol) is the active chemical component of the plant Centella asiatica. Asiaticoside is used to study potential treatments for wounds and burns.
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HALOFUGINONE LACTATE
HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. febrifuga.Halofuginone inhibits prolyl-tRNA synthetase in an ATP-dependent manner with a Ki of 18.3 nM.?Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activityhalofuginone (HF), a widely studied derivative of febrifugine, inhibits the development of T(H)17-driven autoimmunity in a mouse model of multiple sclerosis by activating the amino acid response (AAR) pathway.?HF binds glutamyl-prolyl-tRNA synthetase (EPRS), inhibiting prolyl-tRNA synthetase activity;?this inhibition is reversed by the addition of exogenous proline or EPRS.
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Elinafide
Elinafide, a dinaphthylimide cytotoxic agent, is a DNA-targeted anticancer agent that has shown antitumor activity in in vitro and in vivo assays.
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