(R)-HTS-3
CAS No. 2771208-83-2
(R)-HTS-3( —— )
Catalog No. M37535 CAS No. 2771208-83-2
(R)-HTS-3, a lysophosphatidylcholinacyltransferase 3 (LPCAT3) inhibitor, remodels polyunsaturated phospholipid content in human cells and reduces RSL3-induced ferroptosis in cancer cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 103 | In Stock |
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| 5MG | 155 | In Stock |
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| 10MG | 250 | In Stock |
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| 25MG | 424 | In Stock |
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| 50MG | 600 | In Stock |
|
| 100MG | 824 | In Stock |
|
| 200MG | 1135 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name(R)-HTS-3
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NoteResearch use only, not for human use.
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Brief Description(R)-HTS-3, a lysophosphatidylcholinacyltransferase 3 (LPCAT3) inhibitor, remodels polyunsaturated phospholipid content in human cells and reduces RSL3-induced ferroptosis in cancer cells.
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Description(R)-HTS-3, a lysophosphatidylcholinacyltransferase 3 (LPCAT3) inhibitor, remodels polyunsaturated phospholipid content in human cells and reduces RSL3-induced ferroptosis in cancer cells.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorAcyltransferase
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Research Area——
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Indication——
Chemical Information
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CAS Number2771208-83-2
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Formula Weight304.33
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Molecular FormulaC17H18F2N2O
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Purity>98% (HPLC)
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Solubility——
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SMILES[C@@H](CNC(=O)C1=CC(F)=CC(F)=C1)(N(C)C)C2=CC=CC=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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TMN355
TMN355 is a potent chemical inhibitor of cyclophilin A and reduces foam cell formation and cytokine secretion,and is used for atherosclerosis. Silencing cyclophilin A in THP-1 cells and human monocytes using siRNA or chemical inhibitor, TMN355 resulted in decrease in lipid uptake by 65-75% even after exposure to oxidized LDL.
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Deschloroclozapine
Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist.
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