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Minodronic acid

CAS No. 180064-38-4

Minodronic acid( —— )

Catalog No. M37531 CAS No. 180064-38-4

Minodronic acid(YM-529) is a P2X2/3 receptor antagonist with anticancer activity, directly or indirectly inhibiting the proliferation of cancer cells and inducing apoptosis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 38 In Stock
25MG 61 In Stock
50MG 86 In Stock
100MG 120 In Stock
200MG Get Quote In Stock
500MG 303 In Stock
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Biological Information

  • Product Name
    Minodronic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Minodronic acid(YM-529) is a P2X2/3 receptor antagonist with anticancer activity, directly or indirectly inhibiting the proliferation of cancer cells and inducing apoptosis.
  • Description
    Minodronic acid (YM-529) is a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis, and inhibits metastasis of various types of cancer cells. Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors involved in pain.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    P2X Receptor
  • Recptor
    P2X Receptor | Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    180064-38-4
  • Formula Weight
    322.15
  • Molecular Formula
    C9H12N2O7P2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 5 mg/mL (15.52 mM) DMSO : < 1 mg/mL (insoluble or slightly soluble)
  • SMILES
    OC(Cc1cnc2ccccn12)(P(O)(O)=O)P(O)(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Sato K, et al. A third-generation bisphosphonate, minodronic acid (YM529), successfully prevented the growth of bladder cancer in vitro and in vivo. Br J Cancer. 2006 Nov 20;95(10):1354-61.?
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