Cart
sales@molnova.com
AC-099 hydrochloride
CAS No. 849335-07-5
AC-099 hydrochloride( —— )
Catalog No. M37320 CAS No. 849335-07-5
AC-099 hydrochloride is a selective full agonist of the neuropeptide FF2 receptor NPFF2R (EC50=1189 nM) and partial agonist function of the neuropeptide FF1 receptor NPFF1R (EC50=2370 nM) that reverses opioid-induced nociceptive sensitization, and may be used to study neurological.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 46 | In Stock |
|
| 5MG | 38 | In Stock |
|
| 10MG | 61 | In Stock |
|
| 25MG | 91 | In Stock |
|
| 50MG | 120 | In Stock |
|
| 100MG | 193 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAC-099 hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionAC-099 hydrochloride is a selective full agonist of the neuropeptide FF2 receptor NPFF2R (EC50=1189 nM) and partial agonist function of the neuropeptide FF1 receptor NPFF1R (EC50=2370 nM) that reverses opioid-induced nociceptive sensitization, and may be used to study neurological.
-
DescriptionAC-099 hydrochloride (compound 3) is a selective NPFF2R full agonist (EC50=1189 nM) and NPFF1R partial agonist (EC50=2370 nM). AC-099 hydrochloride attenuates spinal nerve ligation-induced hypersensitivity in rats.
-
In Vitro——
-
In VivoAnimal Model:Male Sprague-Dawley rats (175-300g; spinal nerve ligation (SNL) model).Dosage:30 mg/kg Administration:Intraperitoneal injection; single.Result:Completely attenuated SNL-induced hypersensitivity.
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetNeuropeptide Y Receptor
-
RecptorNeuropeptide Y Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number849335-07-5
-
Formula Weight301.1
-
Molecular FormulaC9H9Cl2F3N4
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCl.FC(F)(F)C1=CC(C=NNC(=N)N)=CC=C1Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Findeisen M, et al. Selective mode of action of guanidine-containing non-peptides at human NPFF receptors. J Med Chem. 2012 Jul 12;55(13):6124-36. ?
molnova catalog
related products
-
Neuropeptide FF
Endogenous antiopioid peptide and agonist at NPFF1 and NPFF2 receptors (Ki values are 2.82 and 0.21 nM respectively).
-
M617
Selective galanin GAL1 receptor agonist (Ki values are 0.23 and 5.71 nM for GAL1 and GAL2 receptors respectively). Enhances food consumption in rats following i.c.v. administration and reduces CAP-induced inflammatory pain.
-
Selvigaltin
Selvigaltin (GB1211) is a Gal-3 inhibitor with potential anticancer activity. Selvigaltin is used in the study of cirrhosis and cancer.
