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AC-099 hydrochloride
CAS No. 849335-07-5
AC-099 hydrochloride( —— )
Catalog No. M37320 CAS No. 849335-07-5
AC-099 hydrochloride is a selective full agonist of the neuropeptide FF2 receptor NPFF2R (EC50=1189 nM) and partial agonist function of the neuropeptide FF1 receptor NPFF1R (EC50=2370 nM) that reverses opioid-induced nociceptive sensitization, and may be used to study neurological.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 46 | In Stock |
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| 5MG | 38 | In Stock |
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| 10MG | 61 | In Stock |
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| 25MG | 91 | In Stock |
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| 50MG | 120 | In Stock |
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| 100MG | 193 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAC-099 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionAC-099 hydrochloride is a selective full agonist of the neuropeptide FF2 receptor NPFF2R (EC50=1189 nM) and partial agonist function of the neuropeptide FF1 receptor NPFF1R (EC50=2370 nM) that reverses opioid-induced nociceptive sensitization, and may be used to study neurological.
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DescriptionAC-099 hydrochloride (compound 3) is a selective NPFF2R full agonist (EC50=1189 nM) and NPFF1R partial agonist (EC50=2370 nM). AC-099 hydrochloride attenuates spinal nerve ligation-induced hypersensitivity in rats.
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In Vitro——
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In VivoAnimal Model:Male Sprague-Dawley rats (175-300g; spinal nerve ligation (SNL) model).Dosage:30 mg/kg Administration:Intraperitoneal injection; single.Result:Completely attenuated SNL-induced hypersensitivity.
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Synonyms——
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PathwayGPCR/G Protein
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TargetNeuropeptide Y Receptor
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RecptorNeuropeptide Y Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number849335-07-5
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Formula Weight301.1
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Molecular FormulaC9H9Cl2F3N4
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.FC(F)(F)C1=CC(C=NNC(=N)N)=CC=C1Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Findeisen M, et al. Selective mode of action of guanidine-containing non-peptides at human NPFF receptors. J Med Chem. 2012 Jul 12;55(13):6124-36. ?
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