Cart
sales@molnova.com
Home - Products - NF-κB - NOD - NT-0796

NT-0796

CAS No. 2272917-13-0

NT-0796( —— )

Catalog No. M37302 CAS No. 2272917-13-0

NT-0796 is a brain-permeable, potent, and selective inhibitor of the inflammasome NLRP3, inhibiting NLRP3 activation.NT-0796 is a potential NDT-19795 delivery vector.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 299 Get Quote
5MG 471 Get Quote
10MG 753 Get Quote
25MG 1546 Get Quote
50MG 2502 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    NT-0796
  • Note
    Research use only, not for human use.
  • Brief Description
    NT-0796 is a brain-permeable, potent, and selective inhibitor of the inflammasome NLRP3, inhibiting NLRP3 activation.NT-0796 is a potential NDT-19795 delivery vector.
  • Description
    NT-0796 is a selective and CNS-penetrant NLRP3 inflammasome inhibitor with an IC50 of 0.32 nM in PBMC assay. NT-0796 is an isopropyl ester that undergoes intracellular conversion to NDT-19795, the carboxylic acid active species. NT-0796 has the potential for neuroinflammatory diseases research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    NF-κB
  • Target
    NOD
  • Recptor
    NOD
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2272917-13-0
  • Formula Weight
    409.48
  • Molecular Formula
    C23H27N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N(C(O[C@H](CC=1N=CC=CN1)C(OC(C)C)=O)=O)C2=C3C(=CC4=C2CCC4)CCC3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. David Harrison, et al. Discovery of Clinical Candidate NT-0796, a Brain-Penetrant and Highly Potent NLRP3 Inflammasome Inhibitor for Neuroinflammatory Disorders. J Med Chem. 2023 Oct 24.?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Nigericin sodium sal...

    Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus and is a NLRP3 activator.

  • NP3-146

    NP3-146 (NLRP3-IN-5) is an inflammasome NLRP3 inhibitor with potential anti-inflammatory activity for the study of autoimmune diseases.

  • NT-0249

    NT-0249 is an orally active inhibitor of the inflammatory vesicle NLRP3 with anti-inflammatory activity that reverses high-fat diet-induced obesity, systemic inflammation, and astrocyte hyperplasia.

Sign In Join Free