NOD-IN-1

CAS No. 132819-92-2

NOD-IN-1( —— )

Catalog No. M11309 CAS No. 132819-92-2

A potent, dual inhibitor of NOD1 and NOD2 with IC50 of 5.74 uM and 6.45 uM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 113 In Stock
10MG 186 In Stock
25MG 312 In Stock
50MG 464 In Stock
100MG 672 In Stock
500MG 1404 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    NOD-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, dual inhibitor of NOD1 and NOD2 with IC50 of 5.74 uM and 6.45 uM, respectively.
  • Description
    A potent, dual inhibitor of NOD1 and NOD2 with IC50 of 5.74 uM and 6.45 uM, respectively; is 7-fold less potent than Noditinib-1 in terms of NOD1 inhibition and completely devoid of selective activity for NOD1 or NOD2 as opposed to Noditinib-1.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    NF-κB
  • Target
    NOD
  • Recptor
    NOD1|NOD2
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    132819-92-2
  • Formula Weight
    343.3969
  • Molecular Formula
    C18H17NO4S
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C(C(N1S(=O)(C2=CC=C(C)C=C2)=O)=CC3=C1C=CC=C3)OCC
  • Chemical Name
    1H-Indole-2-carboxylic acid, 1-[(4-methylphenyl)sulfonyl]-, ethyl ester

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ke?ek Ple?ec K, et al. Bioorg Med Chem. 2016 Nov 1;24(21):5221-5234.
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