DNA polymerase-IN-1

CAS No. 809234-33-1

DNA polymerase-IN-1( —— )

Catalog No. M37273 CAS No. 809234-33-1

DNA polymerase-IN-1, a DNA polymerase inhibitor, exhibited antiproliferative activity against tumor cells with a half-inhibitory concentration (IC50) of 20.7 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 459 In Stock
10MG 657 In Stock
25MG 1026 In Stock
50MG 1386 In Stock
100MG 1832 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    DNA polymerase-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    DNA polymerase-IN-1, a DNA polymerase inhibitor, exhibited antiproliferative activity against tumor cells with a half-inhibitory concentration (IC50) of 20.7 μM.
  • Description
    DNA polymerase-IN-1 (compound 2d) is a DNA polymerase inhibitor (IC50=20.7 μM) with antiproliferative activity against tumor cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    DNA/RNA Synthesis | Antiviral
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    809234-33-1
  • Formula Weight
    226.61
  • Molecular Formula
    C10H7ClO4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1OC=2C=C(O)C=C(O)C2C(=C1)CCl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bruna-Haupt EF, et al. Synthesis of Structurally Related Coumarin Derivatives as Antiproliferative Agents. ACS Omega. 2023 Jul 13;8(29):26479-26496.?
molnova catalog
related products
  • Tallimustine HCl

    Tallimustine HCl is a DNA inhibitor, an AT-specific alkylated antitumor derivative of diamycin.Tallimustine HCl can be used in severe combined immunodeficiency mouse models of adult myelogenous leukemia, which can be used for the treatment of leukemia.

  • Mithramycin A

    A tricyclic pentaglycosidic, antineoplastic antibiotic from Streptomyces strains that inhibits RNA and protein synthesis by adhering to DNA.

  • Apricitabine

    Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-thiocytidine (dOTC) .