Bupivacaine hydrochloride monohydrate( —— )

Catalog No. M37272 CAS No. 73360-54-0

Bupivacaine hydrochloride monohydrate is a potent NMDA receptor inhibitor of sodium, L-calcium, and potassium channels.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Bupivacaine hydrochloride monohydrate
Note

Research use only, not for human use.
Brief Description

Bupivacaine hydrochloride monohydrate is a potent NMDA receptor inhibitor of sodium, L-calcium, and potassium channels.
Description

Bupivacaine hydrochloride monohydrate is a NMDA receptor inhibitor. Bupivacaine hydrochloride monohydrate can block sodium, L-calcium, and potassium channels. Bupivacaine hydrochloride monohydrate potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine hydrochloride monohydrate can be used for the research of chronic pain.
In Vitro

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In Vivo

——
Synonyms

——
Pathway

Membrane Transporter/Ion Channel
Target

Sodium Channel
Recptor

Sodium Channel | Potassium Channel | Calcium Channel | NMDAR
Research Area

——
Indication

——

Chemical Information

CAS Number

73360-54-0
Formula Weight

342.9
Molecular Formula

C18H31ClN2O2
Purity

>98% (HPLC)
Solubility

——
SMILES

Cl.O=C(NC=1C(=CC=CC1C)C)C2N(CCCC)CCCC2.O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Meaghan A Paganelli, et al. Actions of Bupivacaine, a widely used local anesthetic, on NMDA receptor responses. J Neurosci. 2015 Jan 14;35(2):831-42.?

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