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Bupivacaine hydrochloride monohydrate

CAS No. 73360-54-0

Bupivacaine hydrochloride monohydrate( —— )

Catalog No. M37272 CAS No. 73360-54-0

Bupivacaine hydrochloride monohydrate is a potent NMDA receptor inhibitor of sodium, L-calcium, and potassium channels.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Bupivacaine hydrochloride monohydrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Bupivacaine hydrochloride monohydrate is a potent NMDA receptor inhibitor of sodium, L-calcium, and potassium channels.
  • Description
    Bupivacaine hydrochloride monohydrate is a NMDA receptor inhibitor. Bupivacaine hydrochloride monohydrate can block sodium, L-calcium, and potassium channels. Bupivacaine hydrochloride monohydrate potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine hydrochloride monohydrate can be used for the research of chronic pain.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Sodium Channel
  • Recptor
    Sodium Channel | Potassium Channel | Calcium Channel | NMDAR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    73360-54-0
  • Formula Weight
    342.9
  • Molecular Formula
    C18H31ClN2O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.O=C(NC=1C(=CC=CC1C)C)C2N(CCCC)CCCC2.O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Meaghan A Paganelli, et al. Actions of Bupivacaine, a widely used local anesthetic, on NMDA receptor responses. J Neurosci. 2015 Jan 14;35(2):831-42.?
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