Cart
sales@molnova.com
Bintrafusp alfa
CAS No. 1918149-01-5
Bintrafusp alfa( —— )
Catalog No. M37267 CAS No. 1918149-01-5
Bintrafusp alfa (M7824) is a bifunctional fusion protein consisting of the extracellular structural domain of TGF-βRII (a TGF-β “trap”) fused to a monoclonal antibody against human immunoglobulin G1 fused to programmed death ligand 1 (PD-L1).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 400 | Get Quote |
|
| 5MG | 655 | Get Quote |
|
| 10MG | 1026 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameBintrafusp alfa
-
NoteResearch use only, not for human use.
-
Brief DescriptionBintrafusp alfa (M7824) is a bifunctional fusion protein consisting of the extracellular structural domain of TGF-βRII (a TGF-β “trap”) fused to a monoclonal antibody against human immunoglobulin G1 fused to programmed death ligand 1 (PD-L1).
-
DescriptionBintrafusp alfa (M 7824) is a first-in-class bifunctional fusion protein composed of the extracellular domain of TGF-βRII fused to a human IgG1 mAb blocking programmed cell death ligand. Bintrafusp alfa can be used for the research of cancer.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorTGF-beta/Smad
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1918149-01-5
-
Formula Weight
-
Molecular Formula——
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Strauss J, et, al. Bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in patients with human papillomavirus-associated malignancies. J Immunother Cancer. 2020 Dec;8(2):e001395.?
molnova catalog
related products
-
ELA-14 (human)
Potent apelin (APJ) receptor agonist (Ki = 0.93 nM). Bioactive fragment of ELA-32. Activates Gαi1 pathway and β-arrestin-2 recruitment. Reduces arterial pressure in rat hearts. Active in vivo.
-
Cefazedone
Cefazedone is a semisynthetic first-generation cephalosporin?with activity against Gram-positive and Gram-negative bacteria.
-
trans-2-Hexen-1-ol
trans-2-Hexen-1-ol is a natural product for research related to life sciences.
