EGFR/ErbB-2 inhibitor-1

CAS No. 1135150-79-6

EGFR/ErbB-2 inhibitor-1( —— )

Catalog No. M37253 CAS No. 1135150-79-6

EGFR/ErbB-2 inhibitor-1 is a selective ErbB2/HER2 inhibitor that effectively blocks ErbB2 and HER2 signaling.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 321 In Stock
10MG 459 In Stock
25MG 718 In Stock
50MG 958 In Stock
100MG 1274 In Stock
200MG 1721 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    EGFR/ErbB-2 inhibitor-1
  • Note
    Research use only, not for human use.
  • Brief Description
    EGFR/ErbB-2 inhibitor-1 is a selective ErbB2/HER2 inhibitor that effectively blocks ErbB2 and HER2 signaling.
  • Description
    EGFR/ErbB-2 inhibitor-1 is a ErbB2/HER2 inhibitor.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    EGFR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1135150-79-6
  • Formula Weight
    467.97
  • Molecular Formula
    C23H15ClFN3OS2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    FC1=CC=CC(=C1)COC2=CC=C(C=C2Cl)NC=3N=CN=C4SC(=CC43)C=5SC=CC5
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Rheault TR, et al. Thienopyrimidine-based dual EGFR/ErbB-2 inhibitors. Bioorg Med Chem Lett. 2009 Feb 1;19(3):817-20.?
molnova catalog
related products
  • Oritinib

    Oritinib is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q), EGFR (L858R/T790M), EGFR (d746-750), EGFR (d746-750/T790M), respectively. Oritinib can be used in studies about the treatment of non-small cell lung cancer.

  • Cloperastine fendizo...

    Cloperastine fendizoate (Hustazol) inhibits the hERG K+ currents in a concentration-dependent manner (IC50: 27 nM).

  • NRC-2694

    NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.