Tyrphostin A25( —— )

Catalog No. M33749 CAS No. 118409-58-8

Tyrphostin A25 (Tyrphostin AG 82) is a specific EGFR tyrosine kinase inhibitor and GPR35 agonist with an IC50 value of 0.94 μM for GPR35 and an EC50 value of 5.3 μM for GPR35.

Purity : >98% (HPLC)

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HNMR

HPLC

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Biological Information

Product Name

Tyrphostin A25
Note

Research use only, not for human use.
Brief Description

Tyrphostin A25 (Tyrphostin AG 82) is a specific EGFR tyrosine kinase inhibitor and GPR35 agonist with an IC50 value of 0.94 μM for GPR35 and an EC50 value of 5.3 μM for GPR35.
Description

Tyrphostin 25 (AG82) is a specific inhibitor of the EGFR tyrosine kinase. Tyrphostin 25 is also a GPR35 agonist with an IC50 of 0.94 μM and an EC50 of 5.3 μM.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

EGFR
Recptor

EGFR | GPR
Research Area

——
Indication

——

Chemical Information

CAS Number

118409-58-8
Formula Weight

202.17
Molecular Formula

C10H6N2O3
Purity

>98% (HPLC)
Solubility

——
SMILES

C(=C(C#N)C#N)C1=CC(O)=C(O)C(O)=C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Klemke RL, et al. Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin. J Cell Biol. 1994 Nov;127(3):859-66. ?

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