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Lotiglipron
CAS No. 2401892-75-7
Lotiglipron( —— )
Catalog No. M37118 CAS No. 2401892-75-7
Lotiglipron (PF-07081532) is an orally active, potent GLP-1R agonist that reduces blood glucose and body weight, potentially aiding in the study of type 2 diabetes mellitus (T2DM) and obesity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 136 | In Stock |
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| 10MG | 207 | In Stock |
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| 25MG | 416 | In Stock |
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| 50MG | 612 | In Stock |
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| 100MG | 918 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameLotiglipron
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NoteResearch use only, not for human use.
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Brief DescriptionLotiglipron (PF-07081532) is an orally active, potent GLP-1R agonist that reduces blood glucose and body weight, potentially aiding in the study of type 2 diabetes mellitus (T2DM) and obesity.
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DescriptionLotiglipron (PF-07081532) is an orally active GLP-1R agonist. Lotiglipron reduces glucose and body weight, and can be used for research of Type 2 diabetes mellitus (T2DM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetGlucagon Receptor
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RecptorGlucagon Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number2401892-75-7
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Formula Weight575.05
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Molecular FormulaC31H31ClN4O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (217.37 mM; Ultrasonic )
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SMILESC[C@]1(OC2=C(C=CC=C2O1)C3CCN(CC=4N(C[C@@H]5CCO5)C=6C(N4)=CC=C(C(O)=O)C6)CC3)C7=CC=C(Cl)C=N7
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Buckeridge C, et al. Once-daily oral small molecule GLP-1R agonist PF-07081532 reduces glucose and body weight within 4-6 weeks in adults with type 2 diabetes and non-diabetic adults with obesity. Hybrid 58th EASD Annual Meeting; Sept 19–23, 2022 (abstr 114).
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