KP-457

CAS No. 1365803-52-6

KP-457( —— )

Catalog No. M37116 CAS No. 1365803-52-6

KP-457 is a specific inhibitor of a disintegrin-metalloproteinase 17 (ADAM17) and a TNFα converting enzyme TACE inhibitor that blocks the production of soluble TNF (sTNF).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 231 In Stock
5MG 217 In Stock
10MG 353 In Stock
25MG 655 In Stock
50MG 1014 In Stock
100MG 1376 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    KP-457
  • Note
    Research use only, not for human use.
  • Brief Description
    KP-457 is a specific inhibitor of a disintegrin-metalloproteinase 17 (ADAM17) and a TNFα converting enzyme TACE inhibitor that blocks the production of soluble TNF (sTNF).
  • Description
    KP-457 is a specific inhibitor of a disintegrin-metalloproteinase 17 (ADAM17) and a TNFα converting enzyme TACE inhibitor that blocks the production of soluble TNF (sTNF).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    MMP
  • Recptor
    MMP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1365803-52-6
  • Formula Weight
    480.56
  • Molecular Formula
    C21H24N2O7S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(CS(=O)(=O)C1=CC=C(OCC#CC)C=C1)(N(C=O)O)C2=CC=C(CNS(C)(=O)=O)C=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
related products
  • 2,3-Dihydrohinokifla...

    2,3-Dihydrohinokiflavone is a suppressor of matrix metalloproteinases (MMP) gene expression and shows strong activity against Leishmania with an IC50 of 1.6 μM.

  • isomer-CM 352

    isomer-CM 352 is a metalase inhibitor that can be used to slow brain damage.

  • MMP-12 Inhibitor

    MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.