FSEN1( —— )

Catalog No. M37112 CAS No. 862808-01-3

FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

FSEN1
Note

Research use only, not for human use.
Brief Description

FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM.
Description

FSEN1 is a potent and non-competitive FSP1 inhibitor with an IC50 value of 313 nM. FSEN1 triggers iron death in cancer cells by inhibiting FSP1. FSEN1 can be used in research of cancer.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Apoptosis
Target

Ferroptosis
Recptor

Ferroptosis
Research Area

——
Indication

——

Chemical Information

CAS Number

862808-01-3
Formula Weight

484.41
Molecular Formula

C22H22BrN5OS
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 5 mg/mL (10.32 mM; Ultrasonic (<60°C); DMF : ≥ 1 mg/mL (2.06 mM)
SMILES

COC1=CC=C(C=C1)N1CCN(CC2=CN3C(S2)=NN=C3C2=CC=C(Br)C=C2)CC1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Hendricks JM, et, al. Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis. Cell Chem Biol. 2023 May 4:S2451-9456(23)00114-9.?

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