Muvalaplin( —— )

Catalog No. M37059 CAS No. 2565656-70-2

Muvalaplin (LY3473329) is an orally active lipoprotein (a) [Lp(a)] reagent that inhibits Lp(a) formation by blocking apo(a)-apo B100 interactions.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Muvalaplin
Note

Research use only, not for human use.
Brief Description

Muvalaplin (LY3473329) is an orally active lipoprotein (a) [Lp(a)] reagent that inhibits Lp(a) formation by blocking apo(a)-apo B100 interactions.
Description

Muvalaplin (LY3473329) is an orally active reagent of lipoprotein (a) (Lp (a)). At present, research on Muvalaplin oral reagent is ongoing.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

2565656-70-2
Formula Weight

710.9
Molecular Formula

C42H54N4O6
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 22.73 mg/mL (31.97 mM; ultrasonic and adjust pH to 3 with 1M HCl; H2O : < 0.1 mg/mL (insoluble)
SMILES

[C@@H](CC1=CC(CN(CC2=CC(C[C@H](C(O)=O)[C@]3(CCNC3)[H])=CC=C2)CC4=CC(C[C@H](C(O)=O)[C@]5(CCNC5)[H])=CC=C4)=CC=C1)(C(O)=O)[C@]6(CCNC6)[H]
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Bhatia HS, et al. Lipoprotein(a): Evidence for Role as a Causal Risk Factor in Cardiovascular Disease and Emerging Therapies. J Clin Med. 2022 Oct 13;11(20):6040.?

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