Cart
sales@molnova.com
TNKS-2-IN-1
CAS No. 4765-59-7
TNKS-2-IN-1( —— )
Catalog No. M37041 CAS No. 4765-59-7
TNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity against E. coli and S. aureus.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 28 | In Stock |
|
| 25MG | 40 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameTNKS-2-IN-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionTNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity against E. coli and S. aureus.
-
DescriptionTNKS-2-IN-1 (Compound 13g) is a TNKS-2 inhibitor. TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayWnt/Notch/Hedgehog
-
TargetWnt/beta/catenin
-
RecptorWnt/beta-catenin | PARP | Antibiotic
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number4765-59-7
-
Formula Weight267.24
-
Molecular FormulaC14H9N3O3
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 1 mg/mL (3.74 mM; Ultrasonic (<60°C)
-
SMILES[O-][N+](=O)c1ccc(cc1)-c1nc(=O)c2ccccc2[nH]1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Nathubhai A, et al. Structure-activity relationships of 2-arylquinazolin-4-ones as highly selective and potent inhibitors of the tankyrases. Eur J Med Chem. 2016 Aug 8;118:316-27.?
molnova catalog
related products
-
NRX-252114 B
NRX-252114 (NRX252114) induces degradation of mutant β-catenin NRX-252114 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP, and is able to enhance the binding of pSer33/S37A β-catenin to β-TrCP with an EC50 of 6.5 nM and a Kd of 0.4 nM. Kd is 0.4 nM.
-
Cardiogenol C hydroc...
Cardiogenol C hydrochloride can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).
-
KY02111
KY02111 promotes differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling.
