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TINK-IN-1

CAS No. 1417795-25-5

TINK-IN-1( —— )

Catalog No. M37028 CAS No. 1417795-25-5

TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Size	Price / USD	Stock	Quantity
2MG	46	In Stock
5MG	75	In Stock
10MG	123	In Stock
25MG	250	In Stock
50MG	365	In Stock
100MG	535	In Stock
200MG	Get Quote	In Stock
500MG	1135	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

TINK-IN-1
Note

Research use only, not for human use.
Brief Description

TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.
Description

TINK-IN-1 (Compound 9) is a potent and selective Traf2- and Nck-interacting kinase (TNIK) inhibitor with an IC50 of 8 nM. TINK-IN-1 inhibits colorectal cancer cells viability.
In Vitro

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In Vivo

——
Synonyms

——
Pathway

Wnt/Notch/Hedgehog
Target

Wnt/beta/catenin
Recptor

Wnt/beta-catenin
Research Area

——
Indication

——

Chemical Information

CAS Number

1417795-25-5
Formula Weight

416.47
Molecular Formula

C24H24N4O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (300.14 mM; Ultrasonic )
SMILES

N#CC=1C=CC(OC)=C(C1)C=2C=CN=C(C2)NC3=CC=C(C(OC)=C3)N4CCOCC4
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Ho KK, et al. Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. Bioorg Med Chem Lett. 2013 Jan 15;23(2):569-73.?

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