h-NTPDase-IN-4

CAS No. 2939933-09-0

h-NTPDase-IN-4( —— )

Catalog No. M37029 CAS No. 2939933-09-0

h-NTPDase-IN-4 is a pan-inhibitor of NTPDase, which can inhibit h-NTPDase1, 1h-NTPDase2, h-NTPDase3, h-NTPDase8. The IC50 values were 3.58 μM, 10.21 μM, 0.13 μM and 13.57 μM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 140 In Stock
10MG 224 In Stock
25MG 449 In Stock
50MG 704 In Stock
100MG 918 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    h-NTPDase-IN-4
  • Note
    Research use only, not for human use.
  • Brief Description
    h-NTPDase-IN-4 is a pan-inhibitor of NTPDase, which can inhibit h-NTPDase1, 1h-NTPDase2, h-NTPDase3, h-NTPDase8. The IC50 values were 3.58 μM, 10.21 μM, 0.13 μM and 13.57 μM, respectively.
  • Description
    h-NTPDase-IN-4 (compound 4c) is a pan-inhibitor of NTPDase with IC50s of 3.58 μM (h-NTPDase1), 10.21 μM (h-NTPDase2), 0.13 μM (h-NTPDase3), 13.57 μM (h- NTPDase8).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Phosphatase
  • Recptor
    Phosphatase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2939933-09-0
  • Formula Weight
    560.36
  • Molecular Formula
    C22H8F12N2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMF : 100 mg/mL (178.46 mM; Ultrasonic)
  • SMILES
    C(F)(F)(F)C=1C=C(C2=C3C(C(=CS3)C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)=NC=N2)C=C(C(F)(F)F)C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zaman G, Ullah S, Uzair M, et al. Synthesis of Thieno [3, 2‐d] pyrimidine Derivatives through Sequential SNAr and Suzuki Reactions as Selective h‐NTPDases Inhibitors[J]. ChemMedChem, 2023: e202300165.
molnova catalog
related products
  • SHP099 monohydrochlo...

    SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor.

  • KY-226

    KY-226 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B)(IC50: 0.25 μM)

  • CCT007093

    CCT007093 is a potent PPM1D (WIP1) inhibitor with IC50 of 8.4 μM.