JC-229
CAS No. 3026716-22-0
JC-229( —— )
Catalog No. M37015 CAS No. 3026716-22-0
JC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. JC-229 can be used to study human African Trypanosomiasis (HAT).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 64 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameJC-229
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NoteResearch use only, not for human use.
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Brief DescriptionJC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. JC-229 can be used to study human African Trypanosomiasis (HAT).
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DescriptionJC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. JC-229 can be used to study human African Trypanosomiasis (HAT).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetTRP/TRPV Channel
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RecptorTRP/TRPV Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number3026716-22-0
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Formula Weight504.21
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Molecular FormulaC20H14Cl4N2O3S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NC1=CC=C(Cl)C(Cl)=C1)C2=CC=C(C(=C2)S(=O)(=O)NC3=CC=C(Cl)C(Cl)=C3)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Capsazepine
Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM).?Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of chilli pepper) which activates the TRPV1 ion channel.?It is therefore considered to be a capsaicin antagonist.
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Probenecid
The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate.
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AMG-0347
AMG-0347 (UNII-CD7L9290QR) is a small molecule inhibitor targeting TRPA1(transient receptor potential ankyrin 1) ion channels, a receptor found in sensory neurons and involved in the detection of pain and environmental stimuli. AMG-0347 acts by blocking the function of TRPA1 and has analgesic effects.
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