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Bisindolylmaleimide III

CAS No. 137592-43-9

Bisindolylmaleimide III( —— )

Catalog No. M37001 CAS No. 137592-43-9

Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC), specifically interacting with PKCα or ribosomal S6 protein kinase 1 upon activation of these kinases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 74 In Stock
5MG 67 In Stock
10MG 110 In Stock
25MG 185 In Stock
50MG 269 In Stock
100MG 399 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Bisindolylmaleimide III
  • Note
    Research use only, not for human use.
  • Brief Description
    Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC), specifically interacting with PKCα or ribosomal S6 protein kinase 1 upon activation of these kinases.
  • Description
    Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC). Bisindolylmaleimide III selectively interacts with either PKCα or ribosomal S6 protein kinase 1 after activation of these kinases.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    PKC
  • Recptor
    PKC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    137592-43-9
  • Formula Weight
    384.43
  • Molecular Formula
    C23H20N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (65.03 mM; Ultrasonic )
  • SMILES
    O=C1C(=C(C(=O)N1)C=2C=3C(NC2)=CC=CC3)C=4C=5C(N(CCCN)C4)=CC=CC5
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Brehmer D, et, al. Proteome-wide identification of cellular targets affected by bisindolylmaleimide-type protein kinase C inhibitors. Mol Cell Proteomics. 2004 May;3(5):490-500. ?
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