CP 461
CAS No. 227619-96-7
CP 461( —— )
Catalog No. M34553 CAS No. 227619-96-7
CP 461 (UNII-68OJX9I7DT), a specific PDE2A inhibitor, is a novel pro-apoptotic compound that inhibits cyclic GMP phosphodiesterase but not cyclooxygenase-1 or -2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 245 | In Stock |
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| 10MG | 363 | In Stock |
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| 25MG | 562 | In Stock |
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| 50MG | 759 | In Stock |
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| 100MG | 1014 | In Stock |
|
| 200MG | 1376 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameCP 461
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NoteResearch use only, not for human use.
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Brief DescriptionCP 461 (UNII-68OJX9I7DT), a specific PDE2A inhibitor, is a novel pro-apoptotic compound that inhibits cyclic GMP phosphodiesterase but not cyclooxygenase-1 or -2.
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DescriptionCP 461 (UNII-68OJX9I7DT), a specific PDE2A inhibitor, is a novel pro-apoptotic compound that inhibits cyclic GMP phosphodiesterase but not cyclooxygenase-1 or -2. CP 461 inhibits the growth of a variety of human tumor cell lines in vitro and selectively induces apoptosis in cancer cell lines, but not in normal cells.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis | PDE
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Research Area——
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Indication——
Chemical Information
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CAS Number227619-96-7
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Formula Weight420.91
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Molecular FormulaC25H22ClFN2O
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Purity>98% (HPLC)
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Solubility——
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SMILESC(C(NCC1=CC=CC=C1)=O)C=2C=3C(/C(=C\C=4C=CN=CC4)/C2C)=CC=C(F)C3.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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β-Elemene
β-Elemene is a natural product isolated from Curcuma wenyujin, with an antitumor activity and induce cell apoptosis.β-Elemene significantly inhibited the metastatic capacity of MDR gastric cells in vivo and in vitro.?Mechanistically, β-Elemene regulated MMP-2/9 expression and reversed epithelial-mesenchymal transition.?
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Juglanin
Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.
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1-beta-D-Arabinofura...
1-beta-D-Arabinofuranosylthymine (Thymine 1-β-D-arabinofuranoside) is a purine nucleoside analog. Purine nucleoside analogs have a broad spectrum of antitumor activity, targeting inert lymphoid malignancies and inducing apoptosis.
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