Wnt pathway inhibitor 3

CAS No. 663213-98-7

Wnt pathway inhibitor 3( —— )

Catalog No. M36918 CAS No. 663213-98-7

Wnt pathway inhibitor 3 is a potent AC1 inhibitor (IC50: 45 nM) with antiproliferative activity, suitable for studies to ameliorate osteoarthritis in a mouse model of experimental osteoarthritis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 31 In Stock
25MG 52 In Stock
50MG 74 In Stock
100MG 111 In Stock
200MG 163 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Wnt pathway inhibitor 3
  • Note
    Research use only, not for human use.
  • Brief Description
    Wnt pathway inhibitor 3 is a potent AC1 inhibitor (IC50: 45 nM) with antiproliferative activity, suitable for studies to ameliorate osteoarthritis in a mouse model of experimental osteoarthritis.
  • Description
    Wnt pathway inhibitor 3 is a potent wnt inhibitor with an IC50 value of 45 nM. Wnt pathway inhibitor 3 shows antiproliferative activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Wnt/Notch/Hedgehog
  • Target
    Wnt/beta/catenin
  • Recptor
    Wnt/beta-catenin | Adenylyl cyclase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    663213-98-7
  • Formula Weight
    457.27
  • Molecular Formula
    C21H17BrN2O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(#N)C=1C(C2=C(C=C3C(=C2)OCO3)OC1N)C4=CC(OC)=C(OCC=C)C(Br)=C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Michael Boutros, et al. Chromene derivatives and their analoga as wnt pathway antagonists. US20130296344A1.
molnova catalog
related products
  • Cardiogenol C hydroc...

    Cardiogenol C hydrochloride can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).

  • NRX-252114 B

    NRX-252114 (NRX252114) induces degradation of mutant β-catenin NRX-252114 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP, and is able to enhance the binding of pSer33/S37A β-catenin to β-TrCP with an EC50 of 6.5 nM and a Kd of 0.4 nM. Kd is 0.4 nM.

  • TNKS-2-IN-2

    TNKS-2-IN-2 is a novel and potent TNKS2 selective inhibitor (IC50: 22 nM) with potential anti-tumour activity for studying colon cancer, lung cancer, and breast cancer.