Glembatumumab( —— )

Catalog No. M36895 CAS No. 1020264-78-1

Glembatumumab is a fully human IgG2 monoclonal antibody targeting the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

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Size	Price / USD	Stock	Quantity
2MG	400	Get Quote
5MG	559	Get Quote
10MG	900	Get Quote
25MG	1270	Get Quote
50MG	1739	Get Quote
100MG	2295	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

Glembatumumab
Note

Research use only, not for human use.
Brief Description

Glembatumumab is a fully human IgG2 monoclonal antibody targeting the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma.
Description

Glembatumumab is a fully human IgG2 monoclonal antibody directed against the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma. Glembatumumab can be coupled to the microtubule inhibitor monomethyl auristatin E to form glembatumumab vedotin. Glembatumumab vedotin is an antibody-agent coupling (ADC) with antitumor activity.
In Vitro

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In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

ADC Antibody
Research Area

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Indication

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Chemical Information

CAS Number

1020264-78-1
Formula Weight

Approximately 145.56 kDa
Molecular Formula

——
Purity

>98% (HPLC)
Solubility

——
SMILES

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Chemical Name

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Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Naumovski L, et al. Glembatumumab vedotin, a conjugate of an anti-glycoprotein non-metastatic melanoma protein B mAb and monomethyl auristatin E for the treatment of melanoma and breast cancer. Curr Opin Mol Ther. 2010 Apr;12(2):248-57.?

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