3-O-Acetyl-16 alpha-hydroxytrametenolic acid( —— )

Catalog No. M22054 CAS No. 168293-13-8

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HPLC

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Product Name

3-O-Acetyl-16 alpha-hydroxytrametenolic acid
Note

Research use only, not for human use.
Brief Description

3-O-Acetyl-16 alpha-hydroxytrametenolic acid has inhibitory activities against AAPH-induced hemolysis of red blood cells, it shows a strong inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice.
Description

3-O-Acetyl-16 alpha-hydroxytrametenolic acid has inhibitory activities against AAPH-induced hemolysis of red blood cells, it shows a strong inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice.In this study, tests were carried out to identify the main ingredient of Hoelen that has the scavenging effect on free-radicals. Triterpene carboxylic acids isolated from the methanol extract of Hoelen, i.e. pachymic acid, polyporenic acid, 3-epidehydrotumulosic acid, 3beta-hydroxylanosta-7,9(11), 24-trien-21-oic acid and 3-O-Acetyl-16 alpha-hydroxytrametenolic acid, were found to have inhibitory activities against AAPH-induced lysis of red blood cells.
In Vitro

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In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

Immunology & Inflammation related
Research Area

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Indication

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CAS Number

168293-13-8
Formula Weight

514.8
Molecular Formula

C32H50O5
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 7.14 mg/mL (13.87 mM)
SMILES

[H][C@]1([C@@H](CCC=C(C)C)C(O)=O)[C@H](O)C[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](OC(C)=O)C(C)(C)[C@]1([H])CC3
Chemical Name

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1.Inhibitory effects of triterpenes isolated from Hoelen on free radical-induced lysis of red blood cells.Phytother Res. 2003 Feb;17(2):160-2.

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