Reptoside, which can be extracted from the roots and above-ground parts of Cortex Eucommiae and Ajuga chamaepitys (L.) Schreb, is one of the active cyclic enol ether terpene glycosides of Cortex Eucommiae for the treatment of osteoporosis.

CDK7-IN-3 is a selective CDK7 inhibitor with a KD of 0.059 nM. CDK7-IN-3 shows poor inhibition on CDK2 (Ki=390 nM), CDK9 (Ki=290 nM), CDK12 (Ki=78 nM). CDK7-IN-3 induce apoptosis in tumor cells and has antitumor activity.

5alpha-Hydroxycostic acid possesses anti-angiogenic ability by interfering the VEGF- and Ang2-related pathways, and it may be a good drug candidate.