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STING agonist-30

CAS No. 2951078-67-2

STING agonist-30( —— )

Catalog No. M36613 CAS No. 2951078-67-2

STING agonist-30 is a potent activator of STING-dependent immune responses, demonstrating broad-spectrum antiviral effects against viruses such as HSV (Herpes Simplex Virus), rotavirus, and SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2).

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    STING agonist-30
  • Note
    Research use only, not for human use.
  • Brief Description
    STING agonist-30 is a potent activator of STING-dependent immune responses, demonstrating broad-spectrum antiviral effects against viruses such as HSV (Herpes Simplex Virus), rotavirus, and SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2).
  • Description
    STING agonist-30 is a potent STING agonist. STING agonist-30 exhibits STING-dependent immune activation. STING agonist-30 has extensive inhibitory effects on various viruses, including the herpes simplex virus (HSV), rotavirus, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
  • In Vitro
    Western Blot Analysis Cell Line:HT1080, THP1, BMDMs and MEFs Concentration:2.5, 5, 10, and 20 μM Incubation Time:5 hours Result:Induced obvious dimeric STING bands.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    STING
  • Recptor
    STING | Antifection
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2951078-67-2
  • Formula Weight
    380.31
  • Molecular Formula
    C15H16N4O8
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(C1=CC=C([N+]([O-])=O)O1)NCCCCCNC(C2=CC=C([N+]([O-])=O)O2)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zang R, et, al. Design and syntheses of a bimolecular STING agonist based on the covalent STING antagonist. Eur J Med Chem. 2023 Mar 15;250:115184.?
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