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TPE-MI
CAS No. 1245606-71-6
TPE-MI( —— )
Catalog No. M36594 CAS No. 1245606-71-6
TPE-MI (Tetraphenylethene maleimide) is an aggregation-induced luminescent agent that stains living cells, can be used to capture cysteines in exposed unfolded proteins, and detects protein damage after dihydroartemisinin studies of malaria parasites.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 128 | In Stock |
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| 5MG | 117 | In Stock |
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| 10MG | 187 | In Stock |
|
| 25MG | 376 | In Stock |
|
| 50MG | 592 | In Stock |
|
| 100MG | 918 | In Stock |
|
| 200MG | 1237 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTPE-MI
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NoteResearch use only, not for human use.
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Brief DescriptionTPE-MI (Tetraphenylethene maleimide) is an aggregation-induced luminescent agent that stains living cells, can be used to capture cysteines in exposed unfolded proteins, and detects protein damage after dihydroartemisinin studies of malaria parasites.
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DescriptionTPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells. TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum .
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1245606-71-6
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Formula Weight441.52
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Molecular FormulaC31H23NO2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 44.15 mg/mL (100.00 mM; Ultrasonic )
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SMILESO=C1C=CC(=O)N1C2=CC=C(C=C2)C(C=3C=CC=CC3)=C(C=4C=CC=CC4)C5=CC=C(C=C5)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chen MZ, et al. A thiol probe for measuring unfolded protein load and proteostasis in cells. Nat Commun. 2017;8(1):474. Published 2017 Sep 7. ?
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