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TPE-MI

CAS No. 1245606-71-6

TPE-MI( —— )

Catalog No. M36594 CAS No. 1245606-71-6

TPE-MI (Tetraphenylethene maleimide) is an aggregation-induced luminescent agent that stains living cells, can be used to capture cysteines in exposed unfolded proteins, and detects protein damage after dihydroartemisinin studies of malaria parasites.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	128	In Stock
5MG	117	In Stock
10MG	187	In Stock
25MG	376	In Stock
50MG	592	In Stock
100MG	918	In Stock
200MG	1237	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

TPE-MI
Note

Research use only, not for human use.
Brief Description

TPE-MI (Tetraphenylethene maleimide) is an aggregation-induced luminescent agent that stains living cells, can be used to capture cysteines in exposed unfolded proteins, and detects protein damage after dihydroartemisinin studies of malaria parasites.
Description

TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells. TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum .
In Vitro

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In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

1245606-71-6
Formula Weight

441.52
Molecular Formula

C31H23NO2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 44.15 mg/mL (100.00 mM; Ultrasonic )
SMILES

O=C1C=CC(=O)N1C2=CC=C(C=C2)C(C=3C=CC=CC3)=C(C=4C=CC=CC4)C5=CC=C(C=C5)C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Chen MZ, et al. A thiol probe for measuring unfolded protein load and proteostasis in cells. Nat Commun. 2017;8(1):474. Published 2017 Sep 7. ?

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