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Z16078526

CAS No. 852222-94-7

Z16078526( —— )

Catalog No. M36997 CAS No. 852222-94-7

Z16078526 enhances thermogenesis in mice by inducing endogenous Ucp1 expression, promoting p38 MAPK phosphorylation, and stimulating lipolysis in primary mouse brown adipocytes.

Purity : >98% (HPLC)

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HPLC

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Size	Price / USD	Stock	Quantity
5MG	67	In Stock
10MG	111	In Stock
25MG	236	In Stock
50MG	344	In Stock
100MG	489	In Stock
200MG	672	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Z16078526
Note

Research use only, not for human use.
Brief Description

Z16078526 enhances thermogenesis in mice by inducing endogenous Ucp1 expression, promoting p38 MAPK phosphorylation, and stimulating lipolysis in primary mouse brown adipocytes.
Description

Z16078526 induces endogenous Ucp1 expression, promotes p38 MAPK phosphorylation and lipolysis in primary mouse brown adipocytes. Z16078526 activates thermogenic gene expression and mitochondrial activity (uncoupled respiration) in mouse brown adipocytes. Z16078526 also stimulates thermogenesis in the mouse.
In Vitro

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In Vivo

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Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Mitochondrial Metabolism | p38 MAPK
Research Area

——
Indication

——

Chemical Information

CAS Number

852222-94-7
Formula Weight

371.41
Molecular Formula

C18H17N3O4S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (269.24 mM; Ultrasonic (<80°C)
SMILES

O=C1C=2C(NC(SCC(NC3=C(OC)C=C(OC)C=C3)=O)=N1)=CC=CC2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Vergnes L, et al. Induction of UCP1 and thermogenesis by a small molecule via AKAP1/PKA modulation. J Biol Chem. 2020 Oct 30;295(44):15054-15069.?

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