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Nifurpirinol
CAS No. 13411-16-0
Nifurpirinol( —— )
Catalog No. M36584 CAS No. 13411-16-0
Nifurpirinol (P-7138) is an antimicrobial compound that is acutely toxic to milkfish (Chanos chanos) species.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 79 | In Stock |
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| 5MG | 117 | In Stock |
|
| 10MG | 188 | In Stock |
|
| 25MG | 351 | In Stock |
|
| 50MG | 523 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNifurpirinol
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NoteResearch use only, not for human use.
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Brief DescriptionNifurpirinol (P-7138) is an antimicrobial compound that is acutely toxic to milkfish (Chanos chanos) species.
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DescriptionNifurpirinol (P-7138) is a nitroaromatic antibiotic and acts as a novel substrate for the bacterial nitroreductase (NTR) enzyme. Nifurpirinol is a more potent proagent compared to Metronidazole to trigger cell-ablation in nitroreductase expressing transgenic models.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetTopoisomerase
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RecptorTopoisomerase | Antibiotic | Antibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number13411-16-0
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Formula Weight246.22
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Molecular FormulaC12H10N2O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 20.83 mg/mL (84.60 mM)
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SMILESO=[N+]([O-])C1=CC=C(/C=C/C2=CC=CC(CO)=N2)O1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Cu(II)-Elesclomol
Cu(II)-Elesclomol is a complex formed by the anticancer agent Elesclomol and Cu(II), which selectively transports copper to mitochondria.Cu(II)-Elesclomol has anticancer activity, inhibits the growth of human leukemia K562 cells, and induces cell-cycle arrest, and is used in the study of leukemias.
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Idarubicin
Idarubicin (4-Demethoxydaunorubicin;IMI-30;NSC 256439) is an anthracycline antileukemic that inserts into DNA and prevents DNA unwinding by interfering with the enzyme Topoisomerase II in cancer cells.
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Exatecan Mesylate
Exatecan Mesylate is a DNA topoisomerase I inhibitor (IC50: 2.2 μM, 0.975 μg/mL).Exatecan Mesylate (DX-8951f) significantly inhibits the proliferation of several cancer cell lines, with mean GI50s of 2.02 ng/mL, 2.92 ng/mL, 1.53 ng/mL, and 0.877 ng/mL for breast cancer cells, colon cancer cells, stomach cancer cells and lung cancer cells, respectively.
