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Home - Products - Metabolic Enzyme/Protease - Dehydrogenase - BI?3231

BI?3231

CAS No. 2894848-07-6

BI?3231( —— )

Catalog No. M36527 CAS No. 2894848-07-6

BI 3231 is a selective and potent inhibitor of hydroxysteroid 17 -dehydrogenase 13 HSD17B13, inhibiting hHSD17B13 and mHSD17B13.BI-3231 can be used for the study of alcohol-associated liver injury, fibrosis and cirrhosis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 167 In Stock
5MG 150 In Stock
10MG 236 In Stock
25MG 377 In Stock
50MG 529 In Stock
100MG 731 In Stock
200MG 1014 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    BI?3231
  • Note
    Research use only, not for human use.
  • Brief Description
    BI 3231 is a selective and potent inhibitor of hydroxysteroid 17 -dehydrogenase 13 HSD17B13, inhibiting hHSD17B13 and mHSD17B13.BI-3231 can be used for the study of alcohol-associated liver injury, fibrosis and cirrhosis.
  • Description
    BI 3231 is a potent and selective hydroxysteroid 17 -dehydrogenase 13 (HSD17B13) inhibitor, with IC50s of 1 and 13 nM for hHSD17B13 and mHSD17B13, respectively. BI 3231 has the potential for the research of nonalcoholic steatohepatitis (NASH) and other liver diseases.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Dehydrogenase
  • Recptor
    Dehydrogenase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2894848-07-6
  • Formula Weight
    380.37
  • Molecular Formula
    C16H14F2N4O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (328.63 mM; Ultrasonic (<60°C)
  • SMILES
    O=C1C(=CN(C(=O)N1CC)CC2=NN=C(S2)C=3C=CC(F)=C(O)C3F)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Thamm S, et, al. Discovery of a Novel Potent and Selective HSD17B13 Inhibitor, BI-3231, a Well-Characterized Chemical Probe Available for Open Science. J Med Chem. 2023 Feb 2. ?
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