Cart
sales@molnova.com
Home - Products - Metabolic Enzyme/Protease - Dehydrogenase - BI?3231

BI?3231

CAS No. 2894848-07-6

BI?3231( —— )

Catalog No. M36527 CAS No. 2894848-07-6

BI 3231 is a selective and potent inhibitor of hydroxysteroid 17 -dehydrogenase 13 HSD17B13, inhibiting hHSD17B13 and mHSD17B13.BI-3231 can be used for the study of alcohol-associated liver injury, fibrosis and cirrhosis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 196 Get Quote
5MG 306 Get Quote
10MG 487 Get Quote
25MG 908 Get Quote
50MG 1500 Get Quote
100MG 2367 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    BI?3231
  • Note
    Research use only, not for human use.
  • Brief Description
    BI 3231 is a selective and potent inhibitor of hydroxysteroid 17 -dehydrogenase 13 HSD17B13, inhibiting hHSD17B13 and mHSD17B13.BI-3231 can be used for the study of alcohol-associated liver injury, fibrosis and cirrhosis.
  • Description
    BI 3231 is a potent and selective hydroxysteroid 17 -dehydrogenase 13 (HSD17B13) inhibitor, with IC50s of 1 and 13 nM for hHSD17B13 and mHSD17B13, respectively. BI 3231 has the potential for the research of nonalcoholic steatohepatitis (NASH) and other liver diseases.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Dehydrogenase
  • Recptor
    Dehydrogenase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2894848-07-6
  • Formula Weight
    380.37
  • Molecular Formula
    C16H14F2N4O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (328.63 mM; Ultrasonic (<60°C)
  • SMILES
    O=C1C(=CN(C(=O)N1CC)CC2=NN=C(S2)C=3C=CC(F)=C(O)C3F)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Thamm S, et, al. Discovery of a Novel Potent and Selective HSD17B13 Inhibitor, BI-3231, a Well-Characterized Chemical Probe Available for Open Science. J Med Chem. 2023 Feb 2. ?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • TC HSD 21

    TC HSD 21 is a potent and highly selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM).

  • AGI-6780

    AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant with IC50 of 23 nM.

  • Skepinone-L

    Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor.

Sign In Join Free