(R)-JAK2/STAT3-IN-10a( —— )

Catalog No. M36472 CAS No. 2485758-49-2

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

(R)-JAK2/STAT3-IN-10a
Note

Research use only, not for human use.
Brief Description

(R)-JAK2/STAT3-IN-10a is the R-isomer of JAK2/STAT3-IN-1.JAK2/STAT3-IN-1 is a GP130 D1 structural domain inhibitor with antitumor activity that inhibits the phosphorylation of JAK2 and STAT3. The KD value of (R)-JAK2/STAT3-IN-1 on GP130 protein is 3.8 μM.
Description

(R)-JAK2/STAT3-IN-10a is the R-isomer of JAK2/STAT3-IN-1.JAK2/STAT3-IN-1 is a GP130 D1 structural domain inhibitor with antitumor activity that inhibits the phosphorylation of JAK2 and STAT3. The KD value of (R)-JAK2/STAT3-IN-1 on GP130 protein is 3.8 μM.
In Vitro

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In Vivo

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Synonyms

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Pathway

Immunology/Inflammation
Target

Antiviral
Recptor

Antiviral
Research Area

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Indication

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CAS Number

2485758-49-2
Formula Weight

682.57
Molecular Formula

C34H35BrF3N5O2
Purity

>98% (HPLC)
Solubility

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SMILES

C(N)(=O)N1[C@@H](C=2C=3C(N(CC4=CC=C(OCCN5CCCCCC5)C=C4)C2)=CC=C(Br)C3)CC(=N1)C6=CC=C(C(F)(F)F)C=C6
Chemical Name

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