JAK2/STAT3-IN-1

CAS No. 2485758-50-5

JAK2/STAT3-IN-1( —— )

Catalog No. M36471 CAS No. 2485758-50-5

JAK2/STAT3-IN-1 is a GP130 inhibitor with anti-tumor effects and can be used to study inflammation, autoimmunity and cancer.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 445 Get Quote
5MG 686 Get Quote
10MG 938 Get Quote
25MG 1398 Get Quote
50MG 1822 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    JAK2/STAT3-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    JAK2/STAT3-IN-1 is a GP130 inhibitor with anti-tumor effects and can be used to study inflammation, autoimmunity and cancer.
  • Description
    JAK2/STAT3-IN-1 (compound (S)-10a) is a potent GP130 inhibitor with an IC50 of 3.04 μM. JAK2/STAT3-IN-1 shows anti-tumor activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Interleukin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2485758-50-5
  • Formula Weight
    682.57
  • Molecular Formula
    C34H35BrF3N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(N)(=O)N1[C@H](C=2C=3C(N(CC4=CC=C(OCCN5CCCCCC5)C=C4)C2)=CC=C(Br)C3)CC(=N1)C6=CC=C(C(F)(F)F)C=C6
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Song D, et al. Discovery of bazedoxifene analogues targeting glycoprotein 130. Eur J Med Chem. 2020 Aug 1;199:112375.?
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