JAK2/STAT3-IN-1

CAS No. 2485758-50-5

JAK2/STAT3-IN-1( —— )

Catalog No. M36471 CAS No. 2485758-50-5

JAK2/STAT3-IN-1 is a GP130 inhibitor with anti-tumor effects and can be used to study inflammation, autoimmunity and cancer.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    JAK2/STAT3-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    JAK2/STAT3-IN-1 is a GP130 inhibitor with anti-tumor effects and can be used to study inflammation, autoimmunity and cancer.
  • Description
    JAK2/STAT3-IN-1 (compound (S)-10a) is a potent GP130 inhibitor with an IC50 of 3.04 μM. JAK2/STAT3-IN-1 shows anti-tumor activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Interleukin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2485758-50-5
  • Formula Weight
    682.57
  • Molecular Formula
    C34H35BrF3N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(N)(=O)N1[C@H](C=2C=3C(N(CC4=CC=C(OCCN5CCCCCC5)C=C4)C2)=CC=C(Br)C3)CC(=N1)C6=CC=C(C(F)(F)F)C=C6
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Song D, et al. Discovery of bazedoxifene analogues targeting glycoprotein 130. Eur J Med Chem. 2020 Aug 1;199:112375.?
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